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Understanding the Risks and Side Effects of Stem Cell Therapy for Cerebral Palsy

Thursday, October 16, 2025

  • Cerebral palsy is a complex neurological condition with no cure and limited treatment options.
  • Studies show stem cell therapy can be effective at reducing the symptoms of cerebral palsy.
  • Patients report improved cognition, fewer seizures, and a better range of movement.
  • Despite the potential for this treatment to improve CP symptoms, more research and clinical trials are needed to help patients and providers understand the risks and benefits.

A diagnosis of cerebral palsy (CP) can significantly alter a person’s life trajectory. Brain injuries before birth or during the early stages of life can lead to lifelong disabilities. Children affected by this disease often require assistance or supportive equipment later in life, decreasing their independence. With limited treatment options for CP, the effects can place an undue burden on family members and caregivers.

Stem cell therapy can help CP patients find lasting relief from their symptoms by treating underlying injuries that lead to disability. Consider the risks and benefits of this procedure compared to traditional treatments like surgery, medication, and physical therapy when exploring care options for cerebral palsy.

Why Families Explore Stem Cell Therapy for Cerebral Palsy

Stem cell therapy is bringing new hope to families and individuals with cerebral palsy. Clinical trials have shown that the treatment can dramatically reduce CP symptoms by reducing inflammation and regenerating healthy nerve, muscle, and brain tissue damaged by the disease. Stem cells signal repair in various cell types and activate the body’s immune system. Not every patient has benefited from stem cell therapy, but those who have benefited have experienced significant improvement to the point of becoming somewhat independent (Chahine et al., 2016).

While more research is needed, stem cell therapy offers greater potential benefits and fewer risks than conventional treatments for cerebral palsy. Surgery can correct severe spinal abnormalities after birth, but hip and leg surgeries for children with CP can lead to complications later in life (Dietz et al., 2025). Physical therapy and medications for CP can help manage symptoms by reducing pain and increasing mobility, but they do not address the root causes of disability. Opioids and muscle relaxants can lead to abuse and addiction. They also become less effective over time as the body builds tolerance, requiring higher doses to achieve the same effects.

What Are Stem Cell Therapy's Risks & Side Effects for Cerebral Palsy?

Research on the effects of stem cell therapy is ongoing, but no serious risks or complications have been identified. Unlike conventional treatments, stem cell therapy does not require surgery, implants, or anesthesia. All that is needed is a simple skin biopsy to match the stem cells to your DNA. Mild side effects can include hypoglycemia or fatigue caused by low blood sugar, which is why eating a meal before is encouraged. Patients may also experience irritation or redness around the injection site. The stem cells do not stay in the body and are disposed of naturally to prevent tumors from growing.

How to Choose a Safe Treatment Program

Stem cell therapy is a new and expanding field in the healthcare industry, encompassing a wide range of stem cell types and methods. Treatment should be informed by the latest clinical trials published in peer-reviewed journals. These studies must document the potential benefits and risks so patients understand the effects.

The clinic should have a strong safety record backed up by a history of documenting therapy results and patient outcomes. A quality provider will be transparent about its sources and clearly outline the patient experience and the likelihood of success. Treatment should be tailored to your condition, with localized injections where they will have the most significant impact. Look for an accredited organization that complies with international safety and ethical standards. An independent governing medical authority should oversee all services.

Research and Clinical Trials: What the Evidence Shows

Clinical trials show positive results for cerebral palsy patients undergoing stem cell therapy. Most participants improved significantly across various categories, including spasticity, bowel control, mobility, and independent movement. Forty percent also reported improved cognition (Chahine et al., 2016).

However, many questions remain about the efficacy of stem cell therapy for CP. Many individuals analyzed were children, making it unclear how they will benefit from repeated treatments later in life. The follow-up period also tends to be short, and it’s unclear how long the benefits last (Liu et al., 2021). There are no uniform standards for stem cell therapy, including the dosage, but it’s best to use fresh, not frozen, stem cells cultured in a clean setting that meets international requirements. Thawing stem cells reduces their healing properties.

Families should consider how the stem cells were made and stored, how they will be injected, and how many they will receive per injection. The providers should monitor their progress and stem cell distribution to ensure the therapy has the intended effect.

Making an Informed Decision

The potential for stem cell therapy to help treat cerebral palsy is still being reviewed. Still, research suggests it can relieve symptoms and improve patient outcomes without serious side effects. Families should proceed cautiously when exploring these new treatment options and ask questions about the process, potential risks, and outcomes to ensure they get the best possible care.

Schedule a consultation at Stemaid Institute to learn how stem cell therapy can help with your cerebral palsy.

Frequently Asked Questions

What are stem cell therapy's most common short-term side effects for cerebral palsy?

The most common short-term side effects include low blood sugar, as the body requires glucose to distribute the stem cells. Some may experience a mild fever or irritation around the injection site.

Is stem cell therapy safe for children with CP in the long term?

Yes, stem cell therapy is safe and shows no long-term complications or risks for children with cerebral palsy. Nothing from the treatment stays in the body. Stem cell therapy utilizes the body’s internal healing properties and will not limit the child’s abilities or movements later in life.

What risks should I consider when traveling abroad for stem cell treatment?

Receiving treatment in a facility that does not practice proper sanitation protocols can lead to infection, a risk with all IVs. The clinic should be clean and comply with international care standards to prevent unnecessary complications.

References

1. Treatment of Cerebral Palsy with Stem Cells: A Report of 17 Cases

2. Medium Term Follow-up of Achilles Tendon Lengthening in the Treatment of Ankle Equinus in Cerebral Palsy

3. Progress in clinical trials of stem cell therapy for... : Neural Regeneration Research

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